BIOTOP: An upper domain ontology for the life sciences
BIOTOP: An upper domain ontology for the life sciences
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DOI：
10.3233/ao-2008-0057
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发表时间：
2008-01-01
期刊：
影响因子：
1
通讯作者：
Hahn, Udo
中科院分区：
文献类型：
--
作者：
Beisswanger, Elena;Schulz, Stefan;Hahn, Udo
在生命科学中，对数据的语义互操作性有充分的需求。因此，需要共享词汇表来一致地表达元数据的语义注释以及查询书目信息系统。在过去的几年里，许多高度专业化，但也支离破碎的术语已经演变。然而，它们缺乏概念上相互联系的原则形式。为了提供一个本体论的基础，无缝集成的生物学知识的这些孤立的部分，我们在这里介绍BIOTOP，分子生物学的上域本体。我们描述了它的结构和内容，以及它当前与一组选定的OBO本体的接口，这些本体包含有关分子生物学特定领域的更详细的术语知识，例如，细胞类型、分子功能、生物过程和化学化合物。
In the life sciences, there is an ample need for semantic interoperability of data. Thus shared vocabularies are needed for consistently expressing metadata in terms of semantic annotations as well as for querying bibliographic information systems. In the past years, lots of highly specialized, yet also fragmented terminologies have evolved. However, they lack principled forms of conceptual interlinkage. In order to provide an ontological basis for a seamless integration of such isolated parts of biological knowledge, we here introduce BIOTOP, an upper domain ontology for molecular biology. We describe its structure and contents, as well as its current interfaces to a selected set of OBO ontologies, which contain more detailed terminological knowledge about specific areas of molecular biology, e.g., cell types, molecular functions, biological processes and chemical compounds.