Evaluation of the Swedish National Stroke Campaign: A population-based time-series study
Evaluation of the Swedish National Stroke Campaign: A population-based time-series study
复制标题
DOI：
10.1177/1747493019840939
复制
发表时间：
2019-12-01
影响因子：
6.7
通讯作者：
Rosengren, Lars
中科院分区：
文献类型：
--
作者：
Nordanstig, Annika;Palaszewski, Bo;Rosengren, Lars
背景 从卒中发病到到达医院的时间延迟是再通治疗的一个重要障碍。为了增加对中风症状的了解并尽可能减少延迟到达医院的情况，瑞典开展了为期 27 个月的全国公共信息运动。目的 评估瑞典全国卒中运动的效果。方法 这项全国性研究纳入了 2010 年 10 月 1 日至 2014 年 12 月 31 日（活动开始前一年至活动结束后一年）住院并在瑞典卒中登记处登记的 97,840 名急性卒中患者。终点为 (1) 卒中发作 3 小时内到达医院的患者比例，以及 (2) 接受血管再通治疗的年龄 < 80 岁的患者比例。结果 活动期间，3小时内到达医院的患者比例（p < 0.05）和接受血管再通治疗的患者比例（p < 0.001）均有所增加。这些比例在活动结束后一年保持稳定，并且在活动前一年没有观察到两个终点有显着改善。在比较运动最后一年和运动前一年的多变量逻辑回归模型中，3小时内到达医院的优势比为1.05（95%置信区间（CI）：1.00-1.09），接受血管再通的优势比为1.34（95% CI：1.24-1.46）。结论 瑞典全国中风运动与接受血管再通治疗的患者比例的持续增加以及 3 小时内到达医院的患者比例的小幅但显着的改善相关。
Background Time delay from stroke onset to hospital arrival is an important obstacle to recanalization therapy. To increase knowledge about stroke symptoms and potentially reduce delayed hospital arrival, a 27-month national public information campaign was conducted in Sweden. Aim To assess the effects of a national stroke campaign in Sweden. Methods This nationwide study included 97,840 patients with acute stroke, admitted to hospital and registered in the Swedish Stroke Register from 1 October 2010 to 31 December 2014 (one year before the campaign started to one year after the campaign ended). End points were (1) proportion of patients arriving at hospital within 3 h of stroke onset and (2) the proportion < 80 years of age receiving recanalization therapy. Results During the campaign, both the proportion of patients arriving at hospital within 3 h (p < 0.05) and the proportion receiving recanalization therapy (p < 0.001) increased. These proportions remained stable the year after the campaign, and no significant improvements with respect to the two end points were observed during the year preceding the campaign. In a multivariable logistic regression model comparing the last year of the campaign with the year preceding the campaign, the odds ratio of arriving at hospital within 3 h was 1.05 (95% confidence interval (CI): 1.00-1.09) and that of receiving recanalization was 1.34 (95% CI: 1.24-1.46). Conclusion The Swedish National Stroke Campaign was associated with a sustained increase in the proportion of patients receiving recanalization therapy and a small but significant improvement in the proportion arriving at hospital within 3 h.