Oestrogenic potency of genistin and daidzin in mice.
Oestrogenic potency of genistin and daidzin in mice.
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染料木苷和大豆苷对小鼠的雌激素效力。
DOI：
10.1016/0278-6915(85)90268-6
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
P. Murphy
中科院分区：
文献类型：
--
作者：
E. Farmakalidis;J. Hathcock;P. Murphy
本文研究了染料木苷和大豆苷对B_6D_2F_1小鼠的雌激素活性。己烯雌酚和染料木黄酮用作阳性对照。1.5 mg染料木黄酮的雌激素反应相当于1 mg染料木黄酮，染料木黄酮和染料木黄酮之间的雌激素活性呈1：1的摩尔关系。3.8mg大豆苷的雌激素反应相当于1mg染料木素。在该实验中，对从小鼠获得的血液的分析未能揭示血浆中的任何游离染料木黄酮或大豆苷元。
The oestrogenic activity of genistin and daidzin was investigated in the B6D2F1 strain of mouse. Diethylstilboestrol and genistein were used as positive controls. The oestrogenic response to 1.5 mg genistin was equivalent to that of 1 mg genistein, giving a 1:1 molar relationship in oestrogenic activity between genistin and genistein. The oestrogenic response to 3.8 mg daidzin was equivalent to that of 1 mg genistein. Analysis of the blood obtained from the mice in this experiment failed to reveal any free genistein or daidzein in the plasma.