IMPROVEMENT OF ORAL-MUCOSA WITH MUCIN CONTAINING ARTIFICIAL SALIVA IN GERIATRIC-PATIENTS
IMPROVEMENT OF ORAL-MUCOSA WITH MUCIN CONTAINING ARTIFICIAL SALIVA IN GERIATRIC-PATIENTS
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DOI：
10.1016/0167-4943(92)90054-8
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发表时间：
1992-03-01
影响因子：
4
通讯作者：
WIESEL, K
中科院分区：
文献类型：
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作者：
BLIXTJOHANSEN, G;EK, AC;WIESEL, K
老年人的唾液产量通常减少，导致粘膜干燥，容易受到局部感染，以及其他口腔问题。85名患有多种致残性疾病的住院老年患者参加了一项双盲安慰剂对照研究，研究人员给予含有粘蛋白的人工唾液和安慰剂液体。在接受人工唾液治疗的患者中，口腔粘膜状况有相当大的改善，同时，在接受安慰剂液体治疗的患者中，四分之一的患者口腔念珠菌感染消失，这可能是由于改善了口腔卫生。可以合理地假设，当口腔粘膜状况改善时，总体幸福感会增加。如果导致口干的因素无法消除，即由于疾病或老化因素，使用人工唾液治疗可能是有益的，但良好的口腔卫生的重要性不容忽视。
In elderly individuals the saliva production is often decreased, leading to dry mucosal membranes and predisposition to local infections, as well as other oral problems. Eighty-five hospitalized geriatric patients, with a multitude of disabling diseases, participated in a double blind placebo-controlled study when mucin-containing artificial saliva and a placebo liquid was given. In the patients treated with the artificial saliva a considerable improvement in the condition of oral mucosa was seen, Also, in one quarter of the patients treated with the placebo liquid, the oral candida infection disappeared, possibly due to improved oral hygiene. It is reasonable to assume that general well-being increases when the condition of the oral mucosa improves. If factors causing dry mouth cannot be removed, i.e. due to diseases or ageing factors, treatment with artificial saliva could be of benefit, but the importance of good oral hygiene must not be overlooked.