Tea consumption and myocardial mortality after acute infarction
Tea consumption and myocardial mortality after acute infarction
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DOI：
10.1161/01.cir.0000017201.88994.f7
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发表时间：
2002-05-28
期刊：
影响因子：
37.8
通讯作者：
Mittleman, MA
中科院分区：
文献类型：
--
作者：
Mukamal, KJ;Maclure, M;Mittleman, MA
背景--一些研究表明，饮茶可能与心血管疾病患者的死亡率降低有关，但饮茶对急性心肌梗死后死亡率的影响尚不清楚。方法和结果--作为心肌梗死发病决定因素研究的一部分，我们对1989年至1994年间因确诊急性心肌梗死住院的1900名患者进行了前瞻性队列研究，中位随访时间为3.8年。经过培训的访谈者用标准化问卷评估了梗死前一年自我报告的每周含咖啡因的茶摄入量。我们使用考克斯比例风险回归法比较了不同饮茶量的长期死亡率。在1900名患者中，1019人不喝茶（不喝茶者），615人每周喝茶< 14杯（适度喝茶者），266人每周喝茶14杯或更多（重度喝茶者）。与不饮茶者相比，中度饮茶者（危害比，0.69; 95%CI，0.53 - 0.89）和重度饮茶者（危害比，0.61; 95%CI，0.42 - 0.86）的年龄和性别校正死亡率较低。对临床和社会人口学特征的额外调整并没有明显改变这种关联（中度饮茶者的风险比为0.72; 95%CI为0.55至0.94;重度饮茶者的风险比为0.56; 95%CI为0.37至0.84）。茶和死亡率的关联是相似的总和心血管mortals. Conclusions，自我报告的茶消费量在急性心肌梗死前一年与梗死后死亡率较低。
Background-Some studies have suggested that tea consumption may be associated with lower mortality among individuals with cardiovascular disease, but the effects of tea consumption on mortality after acute myocardial infarction are unknown.Methods and Results-As part of the Determinants of Myocardial Infarction Onset Study, we performed a prospective cohort study of 1900 patients hospitalized with a confirmed acute myocardial infarction between 1989 and 1994, with a median follow-up of 3.8 years. Trained interviewers assessed self-reported usual weekly caffeinated tea consumption during the year before infarction with a standardized questionnaire. We compared long-term mortality according to tea consumption using Cox proportional hazards regression. Of the 1900 patients, 10 19 consumed no tea (nondrinkers), 615 consumed < 14 cups per week (moderate tea drinkers), and 266 consumed 14 or more cups per week (heavy tea drinkers). Compared with nondrinkers, age- and sex-adjusted mortality was lower among moderate tea drinkers (hazard ratio, 0.69; 95% Cl, 0.53 to 0.89) and heavy tea drinkers (hazard ratio, 0.61; 95% Cl, 0.42 to 0.86). Additional adjustment for clinical and sociodemographic characteristics did not appreciably alter this association (hazard ratio, 0.72; 95% Cl, 0.55 to 0.94 for moderate tea drinkers; hazard ratio, 0.56; 95%, Cl, 0.37 to 0.84 for heavy tea drinkers). The association of tea and mortality was similar for total and cardiovascular mortality.Conclusions-Self-reported tea consumption in the year before acute myocardial infarction is associated with lower mortality after infarction.