THE INFLUENCE OF HIGH-FAT DIET ON THE FIBRINOLYTIC-ACTIVITY
THE INFLUENCE OF HIGH-FAT DIET ON THE FIBRINOLYTIC-ACTIVITY
复制标题
DOI：
10.1016/0049-3848(95)91607-m
复制
发表时间：
1995-02-01
影响因子：
7.5
通讯作者：
HWANG, BH
中科院分区：
文献类型：
--
作者：
HO, CH;CHWANG, LC;HWANG, BH
28名中国健康志愿者连续3天给予含50%脂肪的高脂饮食。他们的平均年龄为28.04岁，SD为5.53。分别于进食前、后测定血糖、胆固醇、甘油三酯（TG）和静脉阻断试验（VOT），并于VOT前、后测定组织型纤溶酶原激活物（tPA）和纤溶酶原激活物抑制物（派）。高脂饮食后，血糖、胆固醇显著升高（p分别为0.031、0.049），而其他指标无显著变化。高脂饮食前后，VOT后TPA均显著升高，但高脂饮食后TPA升高幅度明显减小（P
High fat diet containing 50% fat was given to 28 Chinese healthy volunteers for 3 days. Their mean age was 28.04 years with SD 5.53. Blood glucose, cholesterol, triglyceride (TG) and venous occlusion test (VOT) were determined before and after diet, Tissue plasminogen activator (tPA) and plasminogen activator inhibitor (PAI) were determined before and after VOT. After high-fat diet, blood glucose and cholesterol increased significantly (p=0.031, 0.049 respectively), but other parameters did not, TPA increased significantly after VOT either before or after high-fat diet, but such increment was significantly less after high-fat diet (P