Synchrony and Specificity in the Maternal and the Paternal Brain: Relations to Oxytocin and Vasopressin
Synchrony and Specificity in the Maternal and the Paternal Brain: Relations to Oxytocin and Vasopressin
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DOI：
10.1016/j.jaac.2012.06.008
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发表时间：
2012-08-01
影响因子：
13.3
通讯作者：
Feldman, Ruth
中科院分区：
文献类型：
--
作者：
Atzil, Shir;Hendler, Talma;Feldman, Ruth
目的：对养育子女的神经生物学研究已经定义了生物行为同步，即父母和孩子之间生物和行为反应的协调，作为支撑哺乳动物债券形成的中心过程。双亲养育，通常在一夫一妻制的物种中观察到，同样被认为是利用了母亲-父亲同步的机制。方法：我们研究了母亲和父亲的大脑反应的同步性生态有效的婴儿线索。30名母亲和父亲，包括15对夫妇养育4至6个月大的婴儿，被访问的家庭，和婴儿玩录像。然后，父母进行功能性磁共振成像扫描，同时观察自己的婴儿与标准婴儿视频进行比较。使用逐体素算法评估母亲和父亲之间的大脑反应协调，并测试性别特异性激活。血浆催产素和精氨酸加压素，神经肽牵连在女性和男性的结合，作为相关性进行了检查。结果如下：母亲和父亲大脑激活的在线协调出现在涉及同理心和社会认知的社会认知网络中。母亲表现出较高的杏仁核激活和杏仁核反应和催产素之间的相关性。父亲在社会认知回路中表现出更大的激活，这与加压素有关。结论：父母在社会认知网络中协调在线活动，支持对婴儿信号的直观理解和适当的计划，而动机性边缘系统激活可能是性别特异性的。虽然是初步的，但这些发现表明，在依恋关系中，两个人的大脑反应是同步的，这可能表明，人类依恋是在依恋伴侣之间的生物协调和脑对脑同步的矩阵中发展起来的。J. Am. Acad.儿童青少年精神病学，2012;51（8）：798-811.
Objective: Research on the neurobiology of parenting has defined biobehavioral synchrony, the coordination of biological and behavioral responses between parent and child, as a central process underpinning mammalian bond formation. Bi-parental rearing, typically observed in monogamous species, is similarly thought to draw on mechanisms of mother- father synchrony. Method: We examined synchrony in mothers' and fathers' brain response to ecologically valid infant cues. Thirty mothers and fathers, comprising 15 couples parenting 4- to 6-month-old infants, were visited at home, and infant play was videotaped. Parents then underwent functional magnetic resonance imaging scanning while observing own-infant compared with standard-infant videos. Coordination in brain response between mothers and fathers was assessed using a voxel-by-voxel algorithm, and gender-specific activations were also tested. Plasma oxytocin and arginine vasopressin, neuropeptides implicated in female and male bonding, were examined as correlates. Results: Online coordination in maternal and paternal brain activations emerged in social-cognitive networks implicated in empathy and social cognition. Mothers showed higher amygdala activations and correlations between amygdala response and oxytocin. Fathers showed greater activations in social cognitive circuits, which correlated with vasopressin. Conclusions: Parents coordinate online activity in social cognitive networks that support intuitive understanding of infant signals and planning of adequate caregiving, whereas motivational limbic activations may be gender specific. Although preliminary, these findings demonstrate synchrony in the brain response of two individuals within an attachment relationship, and may suggest that human attachment develops within the matrix of biological attunement and brain-to-brain synchrony between attachment partners. J. Am. Acad. Child Adolesc. Psychiatry, 2012;51(8):798-811.