ENZYMATIC HYDROXYLATION OF PROLINE IN MICROSOMAL POLYPEPTIDE LEADING TO FORMATION OF COLLAGEN
ENZYMATIC HYDROXYLATION OF PROLINE IN MICROSOMAL POLYPEPTIDE LEADING TO FORMATION OF COLLAGEN
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DOI：
10.1073/pnas.53.2.335
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发表时间：
1965-01-01
影响因子：
11.1
通讯作者：
UDENFRIEND, S
中科院分区：
文献类型：
--
作者：
PETERKOFSKY, B;UDENFRIEND, S
It has been found that the conversion of unhydroxylated microsomal-bound polypeptide to collagen requires a hydrogen donor, another nonenzymatic factor in the soluble protein fraction and microsomes. Ascorbate or 2-amino-4-hydroxydimethyl-pteridine can serve as the hydrogen donor. Proline hydroxylase appears to be located in the microsomal fraction.
