Acute axonal polyneuropathy associated with anti‐GM1 antibodies following Campylobacter enteritis
Acute axonal polyneuropathy associated with anti‐GM1 antibodies following Campylobacter enteritis
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弯曲杆菌肠炎后与抗 GM1 抗体相关的急性轴突多发性神经病
作者：
N. Yuki;H. Yoshino;S. Sato;T. Miyatake
我们报告2例格林巴利综合征（GBS）后空肠弯曲菌肠炎。电生理研究表明，运动神经的轴突变性是主要过程，临床恢复差。血清检测薄层层析和酶联免疫吸附试验表明，从这两个病人的血清中含有高滴度的抗GM1神经节苷脂的IgG抗体。这些病例可能代表GBS的一个亚组，即与抗GM1抗体相关的空肠弯曲菌肠炎后急性轴突性多发性神经病。
We report 2 patients with Guillain-Barré syndrome (GBS) following Campylobacter jejuni enteritis. Electrophysiologic studies indicated that the predominant process was axonal degeneration of motor nerves, and clinical recovery was poor. Serum testing by thin-layer chromatography and enzyme-linked immunosorbent assay revealed that the sera from both patients contained high titers of IgG antibody against GM1 ganglioside. These cases may represent a subgroup of GBS as acute axonal polyneuropathy following C jejuni enteritis associated with anti-GM1 antibodies.