Activities of daily living and quality of life in persons with newly diagnosed Parkinson's disease according to subtype of disease, and in comparison to healthy controls

Activities of daily living and quality of life in persons with newly diagnosed Parkinson's disease according to subtype of disease, and in comparison to healthy controls
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DOI:
10.1111/j.1600-0404.2010.01344.x
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发表时间:
2011-01-01
影响因子:
3.5
通讯作者:
Forsgren, L.
Forsgren, L.
中科院分区:
医学3区
文献类型:
--
作者:
Hariz, G-M.;Forsgren, L.

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目的-描述日常生活活动(ADL)和生活质量(QoL)在第一次访问的神经中心,在随后诊断为帕金森病(PD)的患者,根据疾病的亚型,并与健康controls.Materials和方法-99例患者和31例对照。根据主要症状将患者分为三组:姿势不稳-步态困难(PIGD)50例,震颤显性37例,不确定12例。评估包括ADL分类,SF-36,和帕金森病问卷(PDQ-39)。结果-患者经历了早期的限制,ADL和生活质量相比,对照组。PIGD亚型的患者已经在第一次访问一个更糟糕的状态,临床和ADL和生活质量,比患者震颤显性type.Conclusions -已经在第一次访问的神经中心,患者谁最终将接受诊断PD表现出限制ADL和生活质量。有轴性症状的患者受影响最大。
Objective -To describe activity of daily living (ADL) and quality of life (QoL) at first visit to a neurological centre, in patients subsequently diagnosed with Parkinson's disease (PD), according to subtype of disease and compared to healthy controls.Materials and methods -99 patients and 31 controls were included. Patients were classified into three groups according to predominant symptoms: 50 Postural instability-gait difficulties (PIGD), 37 tremor dominant, 12 indeterminate. Evaluations included ADL-taxonomy, SF-36, and the Parkinson disease questionnaire (PDQ-39).Results -Patients experienced early on limitations in ADL and QoL compared to controls. Patients with PIGD subtype had already at first visit a worse status, clinically and in ADL and QoL, than patients with tremor dominant type.Conclusions -Already at first visit to a neurological centre, patients who will eventually receive the diagnosis of PD exhibited restrictions in ADL and QoL. Patients with axial symptoms were affected most.