Forebrain noradrenaline and Metrazol-induced seizures.

Forebrain noradrenaline and Metrazol-induced seizures.
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前脑去甲肾上腺素和四唑诱发的癫痫发作。

DOI:
10.1016/0024-3205(78)90266-7
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发表时间:
1978
期刊:
影响因子:
6.1
通讯作者:
M. E. Corcoran
M. E. Corcoran
中科院分区:
医学2区
文献类型:
--
作者:
S. Mason;M. E. Corcoran

文献摘要

被引文献

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前脑去甲肾上腺素在惊厥药物美曲唑引起的癫痫发作中所起的作用,在动物的前脑去甲肾上腺素能束上升纤维中注射6-羟多巴胺进行预处理。在去甲肾上腺素耗尽的动物中发现了癫痫发作持续时间和强度的一致增强。
The role of forebrain noradrenaline in seizures induced by the convulsant drug Metrazol was examined in animals pretreated with injections of 6-hydroxydopamine into the fibers of the ascending noradrenergic bundles. A consistent potentiation of the duration and intensity of the seizures was found in the noradrenaline-depleted animals.