A Randomised Controlled Trial to Reduce Sedentary Time in Young Adults at Risk of Type 2 Diabetes Mellitus: Project STAND (Sedentary Time ANd Diabetes)
A Randomised Controlled Trial to Reduce Sedentary Time in Young Adults at Risk of Type 2 Diabetes Mellitus: Project STAND (Sedentary Time ANd Diabetes)
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DOI：
10.1371/journal.pone.0143398
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发表时间：
2015-12-01
期刊：
影响因子：
3.7
通讯作者：
Davies, Melanie J.
中科院分区：
文献类型：
--
作者：
Biddle, Stuart J. H.;Edwardson, Charlotte L.;Davies, Melanie J.
AIMStype 2糖尿病（T2DM）是一种严重而普遍的慢性疾病，传统上与老年有关。但是，由于肥胖和久坐的生活方式的增长，在年轻人口中越来越被诊断出来。久坐的（坐）行为已被证明与包括T2DM在内的心脏代谢健康结果的更大风险有关。关于减少有T2DM风险的年轻人久坐行为的有效干预措施知之甚少。我们的目的是通过随机对照试验（RCT）设计调查，基于小组的结构化教育研讨会是否专注于减少坐姿，自我监控，减少坐姿。在久坐的时间和糖尿病（Stand）RCT中招募T2DM）或肥胖的其他危险因素。干预计划包括一个基于3小时的组结构教育研讨会，使用自我监控工具和后续励志电话。在三个时间点收集数据：基线，基线3和12个月。主要结局指标是12个月后通过加速度计评估的久坐行为。次要结果包括其他目标（ActivPal）和自我报告的久坐行为和体育活动的度量，以及生化，人体测量学和心理社会变量。回报187个个体（女性为69％；平均年龄33岁；平均BMI 35 kg/m（平均BMI 35 kg/m）（ 2））被随机分为干预组和对照组。 12个月的数据使用意向性治疗分析（ITT）和每项协议分析进行分析时，显示主要结果变量没有显着差异，或者大多数次要结果指标中的大多数差异。在面临T2DM风险的年轻人中，在12个月时改变行为并未成功。缺乏变化可能是由于这种干预的简短性质以及对环境变化的关注。此外，一些参与者报告着专注于体育锻炼，而不是坐着本身的减少。久坐行为的习惯性意味着行为改变是具有挑战性的。
AimsType 2 diabetes mellitus (T2DM), a serious and prevalent chronic disease, is traditionally associated with older age. However, due to the rising rates of obesity and sedentary life-styles, it is increasingly being diagnosed in the younger population. Sedentary (sitting) behaviour has been shown to be associated with greater risk of cardio-metabolic health outcomes, including T2DM. Little is known about effective interventions to reduce sedentary behaviour in younger adults at risk of T2DM. We aimed to investigate, through a randomised controlled trial (RCT) design, whether a group-based structured education workshop focused on sitting reduction, with self-monitoring, reduced sitting time.MethodsAdults aged 18-40 years who were either overweight (with an additional risk factor for T2DM) or obese were recruited for the Sedentary Time ANd Diabetes (STAND) RCT. The intervention programme comprised of a 3-hour group-based structured education workshop, use of a self-monitoring tool, and follow-up motivational phone call. Data were collected at three time points: baseline, 3 and 12 months after baseline. The primary outcome measure was accelerometer-assessed sedentary behaviour after 12 months. Secondary outcomes included other objective (activPAL) and self-reported measures of sedentary behaviour and physical activity, and biochemical, anthropometric, and psycho-social variables.Results187 individuals (69% female; mean age 33 years; mean BMI 35 kg/m(2)) were randomised to intervention and control groups. 12 month data, when analysed using intention-to-treat analysis (ITT) and per-protocol analyses, showed no significant difference in the primary outcome variable, nor in the majority of the secondary outcome measures.ConclusionsA structured education intervention designed to reduce sitting in young adults at risk of T2DM was not successful in changing behaviour at 12 months. Lack of change may be due to the brief nature of such an intervention and lack of focus on environmental change. Moreover, some participants reported a focus on physical activity rather than reductions in sitting per se. The habitual nature of sedentary behaviour means that behaviour change is challenging.