Survival benefit of liver resection for hepatocellular carcinoma associated with portal vein invasion
Survival benefit of liver resection for hepatocellular carcinoma associated with portal vein invasion
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DOI：
10.1016/j.jhep.2016.05.044
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发表时间：
2016-11-01
影响因子：
25.7
通讯作者：
Kokudo, Norihiro
中科院分区：
文献类型：
--
作者：
Kokudo, Takashi;Hasegawa, Kiyoshi;Kokudo, Norihiro
Background & Aims: The presence of portal vein tumor thrombosis (PVTT) in patients with hepatocellular carcinoma (HCC) is regarded as indicating an advanced stage, and liver resection (LR) is not recommended. The aim of this study was to evaluate the survival benefit of LR for HCC patients with PVTT through the analysis of the data from a Japanese nationwide survey.Methods: We analyzed data for 6474 HCC patients with PVTT registered between 2000 and 2007. Of these patients, 2093 patients who underwent LR and 4381 patients who received other treatments were compared. The propensity scores were calculated and we successfully matched 1058 patients (66.1% of the LR group).Results: In the Child-Pugh A patients, the median survival time (MST) in the LR group was 1.77 years longer than that in the non-LR group (2.87 years vs. 1.10 years; p
