THE HISTORY OF CLOZAPINE
THE HISTORY OF CLOZAPINE
复制标题
DOI：
10.1007/bf00442551
复制
发表时间：
1989-01-01
影响因子：
3.4
通讯作者：
HIPPIUS, H
中科院分区：
文献类型：
--
作者：
HIPPIUS, H
氯氮平（CLZ）于20世纪60年代中期首次在欧洲作为一种有效的抗精神病药物进行研究。虽然其化学结构表明CLZ是一种抗抑郁药，但临床研究表明它是一种神经安定药。CLZ在20世纪80年代被美国临床医生重新发现，可能是精神分裂症治疗的先驱。（PsycInfo数据库记录（c）2016阿帕，保留所有权利）
Clozapine (CLZ) was first investigated in Europe in the mid-1960s as a potent antipsychotic drug. Although its chemical structure indicated that CLZ was an antidepressant, clinical investigations showed that it was a neuroleptic. CLZ was rediscovered by US clinicians in the 1980s and may pioneer improvements in the treatment of schizophrenia.(PsycINFO Database Record (c) 2016 APA, all rights reserved)