Gold nanorods with noncovalently tailorable surface for multi-modality image-guided chemo-photothermal cancer therapy
Gold nanorods with noncovalently tailorable surface for multi-modality image-guided chemo-photothermal cancer therapy
复制标题
具有非共价可定制表面的金纳米棒用于多模态图像引导化学光热癌症治疗
DOI：
10.1039/c9cc07131h
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发表时间：
2019
影响因子：
4.9
通讯作者：
Ruibing Wang
中科院分区：
文献类型：
--
作者：
Ludan Yue;Chen Sun;Qian Cheng;Yuanfu Ding;Jianwen Wei;Ruibing Wang
开发了第一个葫芦[7]脲官能化的Au纳米棒，其允许通过强的主客体相互作用用靶向配体和客体药物分子进行非共价可定制的表面修饰。该新型纳米平台在体外和体内均表现出有效的、图像引导的、靶向的化学光热癌症治疗。
The first cucurbit[7]uril functionalized Au nanorods were developed, which allowed noncovalently tailorable surface modification with a targeting ligand and a guest drug molecule, via strong host–guest interactions. The novel nanoplatform exhibited effective, image-guided, targeted chemo-photothermal cancer therapy in vitro and in vivo.