Negative-Pressure Wound Therapy: A Comprehensive Review of the Evidence
Negative-Pressure Wound Therapy: A Comprehensive Review of the Evidence
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DOI：
10.1097/prs.0000000000002645
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发表时间：
2016-09-01
影响因子：
3.6
通讯作者：
Kim, Paul J.
中科院分区：
文献类型：
--
作者：
Anghel, Ersilia L.;Kim, Paul J.
背景：负压伤口治疗（NPWT）及其变体是一种既定的伤口治疗方法。自其推出以来，出版物数量不断增加，在技术创新之后，出版物数量迅速增加。其在不同伤口类型和不同临床场景中的应用也导致了越来越多的publications.Methods：使用PubMed/Medline和奥维德，使用与NPWT最相关的关键词进行全面的文献综述（1998-2016）。合格标准包括更高水平的证据研究。结果：一千三百四十七出版物被确定。本综述共纳入26篇出版物：16篇比较NPWT与标准伤口敷料，6篇比较NPWT的变化，4篇比较NPWT与滴注。证据的水平，伤口类型的研究，报告的结果和影响，以及主要的调查结果列表和discussed.Conclusions：出版物的数量显着增长，因为NPWT的成立。这在一定程度上反映了NPWT的变化。然而，需要更多的可靠的，随机的，前瞻性的研究来支持它的广泛使用。
Background: Negative-pressure wound therapy (NPWT) and its variations are an established adjunctive modality for the treatment of wounds. Since its introduction, there have been an increasing number of publications with periods of rapid increases in the number of publications after innovations to the technology. Its application in different wound types and varying clinical scenarios has also contributed to the growing number of publications.Methods: A comprehensive literature review (1998-2016) was performed using key words most relevant to NPWT using PubMed/Medline and OVID. Eligibility criteria included higher level evidence studies.Results: One thousand three hundred and forty-seven publications were identified. A total of 26 publications are included in this review: 16 comparing NPWT with standard wound dressing, 6 comparing variations of NPWT, and 4 for NPWT with instillation. The level of evidence, wound type studied, reported outcomes and impact, and key findings are tabulated and discussed.Conclusions: The number of publications has grown significantly since the inception of NPWT. In part, this reflects the variations of NPWT that have developed. However, a greater number of robust, randomized, prospective studies are needed to support its wide spread use.