Cysteine and hydrophobic residues in CDR3 serve as distinct T-cell self-reactivity indices
Cysteine and hydrophobic residues in CDR3 serve as distinct T-cell self-reactivity indices
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DOI：
10.1016/j.jaci.2019.03.022
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发表时间：
2019-07-01
影响因子：
14.2
通讯作者：
Notarangelo, Luigi D.
中科院分区：
文献类型：
--
作者：
Daley, Stephen R.;Koay, Hui-Fern;Notarangelo, Luigi D.
Stephen R. Daley，PhDa，Hui-Fern Koay，PhDb，c，Kerry Dobbs，MScd，Marita Bosticardo，PhDd，Rushika C. Wirasinha，PhDa，Francesca Pala，PhDd，Riccardo Castagnoli，MDd，Jared H. Rowe，MD，PhDe，丽莎M. Ott de Bruin，MD，PhDf，Sevgi Keles，MDg，Yu Nee Lee，PhDh，Raz Somech，MD，PhDh，Steven M. Holland，MDd，Ottavia M. Delmonte，MDd，Debbie德雷珀，RN，BSNd，Sandra麦克斯韦，RN，BSNd，Julie Niemela，MSi，Jennifer Stoddard，BSi，Sergio D. Rosenzweig，MD，PhDi，Pietro Luigi Poliani，MD，PhDj，Valentina Capo，PhDk，安娜别墅，MDk，l，Dale I.戈弗雷，PhDb，c，Luigi D. Notarangelo，MDd a澳大利亚墨尔本莫纳什大学莫纳什生物医学发现研究所和生物化学与分子生物学系感染与免疫项目; b澳大利亚墨尔本大学Peter Doherty感染与免疫研究所微生物学与免疫学系; c澳大利亚墨尔本大学墨尔本研究理事会会高级分子成像卓越中心; d临床免疫学和微生物学实验室，学院内研究部，国家过敏和传染病研究所，美国国立卫生研究院，Bethesda，Md; e血液学-肿瘤学部，波士顿儿童医院和Dana Farber癌症研究所，哈佛医学院，马萨诸塞州波士顿; f免疫学部，波士顿儿童医院，哈佛医学院，马萨诸塞州波士顿; gDivision of Pediatric Immunology and Allergy，梅拉姆Medical Faculty，Necmettin Erbakan University，Konya，Turkey; hImmunology Service，Edmond and Lily Safra Children's Hospital Sheba Medical Center，Tel Hashomer，Israel; iImmunology Service，Department of Laboratory Medicine，Clinical Center，National Institutes of Health，Bethesda，Md; j布雷西亚大学分子和转化医学系，病理学单位，布雷西亚，意大利; kSan Raffaele Telethon基因治疗研究所，Istituto di Ricovero e Cura a Carattere Scientific（IRCCS）San Raffaele Scientific Institute，米兰，意大利; stephen.戴利@莫纳什。edu.披露潜在的利益冲突：LD Notarangelo由国家过敏和传染病研究所支持;是临床免疫学杂志，临床免疫学和免疫学前沿杂志的董事会成员;并从UpToDate获得版税。其余作者声明他们没有相关的利益冲突。
Stephen R. Daley, PhDa, Hui-Fern Koay, PhDb, c, Kerry Dobbs, MScd, Marita Bosticardo, PhDd, Rushika C. Wirasinha, PhDa, Francesca Pala, PhDd, Riccardo Castagnoli, MDd, Jared H. Rowe, MD, PhDe, Lisa M. Ott de Bruin, MD, PhDf, Sevgi Keles, MDg, Yu Nee Lee, PhDh, Raz Somech, MD, PhDh, Steven M. Holland, MDd, Ottavia M. Delmonte, MDd, Debbie Draper, RN, BSNd, Sandra Maxwell, RN, BSNd, Julie Niemela, MSi, Jennifer Stoddard, BSi, Sergio D. Rosenzweig, MD, PhDi, Pietro Luigi Poliani, MD, PhDj, Valentina Capo, PhDk, Anna Villa, MDk, l, Dale I. Godfrey, PhDb, c, Luigi D. Notarangelo, MDd aInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia; bDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia; cAustralian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, Australia; dLaboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md; eDivision of Hematology-Oncology, Boston Children’s Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, Mass; fDivision of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, Mass; gDivision of Pediatric Immunology and Allergy, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey; hImmunology Service, Edmond and Lily Safra Children’s Hospital Sheba Medical Center, Tel Hashomer, Israel; iImmunology Service, Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Md; jDepartment of Molecular and Translational Medicine, Pathology Unit, University of Brescia, Brescia, Italy; kSan Raffaele Telethon Institute for Gene Therapy, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan, Italy; stephen. daley@ monash. edu. Disclosure of potential conflict of interest: LD Notarangelo is supported by the National Institute of Allergy and Infectious Diseases; has board memberships with the Journal of Clinical Immunology, Clinical Immunology, and Frontiers in Immunology; and has received royalties from UpToDate. The rest of the authors declare that they have no relevant conflicts of interest.