Performance of a new, HIV/AIDS-targeted quality of life (HAT-QoL) instrument in asymptomatic seropositive individuals
Performance of a new, HIV/AIDS-targeted quality of life (HAT-QoL) instrument in asymptomatic seropositive individuals
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DOI：
10.1023/a:1018464200708
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发表时间：
1997-08-01
影响因子：
3.5
通讯作者：
Shea, JA
中科院分区：
文献类型：
--
作者：
Holmes, WC;Shea, JA
目的：评价一种新的人类免疫缺陷病毒/获得性免疫缺陷综合征（HIV/AIDS）靶向生活质量（QoL）量表在无症状HIV血清阳性人群中的心理测量性能。方法：招募201名城乡hiv血清阳性受试者，根据血清阳性个体在群体过程中提供的内容编制76项生活质量试点量表。来自全部样本（n = 201）的问卷回答被用来确定维度，并将项目数量减少到42。然后对无症状子样本（n = 106）对保留项目的回答进行分析。结果：共确定了9个多项目维度：整体功能（OF）、性功能（SF）、信息披露担忧（DW）、健康担忧（HW）、财务担忧（FW）、HIV控制（HM）、生活满意度（LS）、用药担忧（MC）和提供者信任（PT）。无症状受试者（74%男性，64%非白人，63%同性恋/双性恋）的反应显示，除了PT维度（其中44%的人得分最高）外，没有实质性的下限或上限效应。六个维度的内部一致性系数（Cronbach’s alpha）在0.80 ~ 0.89之间。SF（0.52）、HM（0.67）和MC（0.48）维度的系数较低。利用自我报告的HIV疾病严重程度和社会人口学变量构建效度评估，除SF、MC和PT外，其余维度均存在显著相关（p <或等于0.05）。结论：新工具的五个维度（OF、DW、HW、FW和LS）对无症状HIV血清阳性个体具有良好的心理测量特性。这些维度可能有助于研究无症状、血清阳性个体的生活质量。四个维度（SF， HM， MC和PS）需要对该亚群进行额外的细化。
Objective: to evaluate the psychometric performance of a new human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS)-targeted quality of life (QoL) instrument in asymptomatic HIV-seropositive individuals. Methods: 201 urban and rural, HIV-seropositive subjects were recruited to complete a 76-item pilot QoL measure developed using content provided in group process by seropositive individuals. Questionnaire responses from the full sample (n = 201) were used to identify dimensions and to reduce the number of items to 42. The responses to the retained items were then analysed for the asymptomatic subsample (n = 106). Results: 9 multi-item dimensions were identified: overall function (OF), sexual function (SF), disclosure worries (DW), health worries (HW), financial worries (FW), HIV mastery (HM), life satisfaction (LS), medication concerns (MC) and provider trust (PT). The responses by asymptomatic subjects (74% male, 64% non-White and 63% homosexual/bisexual) revealed no substantial floor or ceiling effects, except for the PT dimension (where 44% were found to have scored the highest score). The internal consistency coefficients (Cronbach's alphas) were between 0.80 and 0.89 for six dimensions. The coefficients were lower for the SF (0.52), HM (0.67) and MC (0.48) dimensions. Construct validity assessments, using self-reported HIV disease-severity and sociodemographic variables, revealed some significant relationships (p less than or equal to 0.05) for all dimensions except SF, MC and PT. Conclusions: the results suggested that five dimensions (OF, DW, HW, FW and LS) from the new instrument have good psychometric properties for asymptomatic HIV-seropositive individuals. These dimensions may be useful in the study of asymptomatic, seropositive individuals' QoL. Four dimensions (SF, HM, MC and PS) require additional refinement for this subpopulation.