EvgA of the two-component signal transduction system modulates production of the YhiUV multidrug transporter in Escherichia coli

EvgA of the two-component signal transduction system modulates production of the YhiUV multidrug transporter in Escherichia coli
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DOI:
10.1128/jb.184.8.2319-2323.2002
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发表时间:
2002-04-01
影响因子:
3.2
通讯作者:
Yamaguchi, A
Yamaguchi, A
中科院分区:
生物学3区
文献类型:
--
作者:
Nishino, K;Yamaguchi, A

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Overexpression of the EvgA regulator of the two-component signal transduction system was previously found to modulate multidrug resistance of Escherichia coli by increasing efflux of drugs (K. Nishino and A. Yamaguchi, J. Bacteriol. 183:1455-1458, 2001). Here we present data showing that EvgA contributes to multidrug resistance through increased expression of the multidrug transporter yhiUV gene.