Effect of lysolecithin and albumin on lecithin-cholesterol acyltransferase activity in human plasma.
Effect of lysolecithin and albumin on lecithin-cholesterol acyltransferase activity in human plasma.
复制标题
溶血卵磷脂和白蛋白对人血浆中卵磷脂胆固醇酰基转移酶活性的影响。
DOI：
10.1093/oxfordjournals.jbchem.a130354
复制
发表时间：
1973
影响因子：
2.7
通讯作者：
T. Nishida
中科院分区：
文献类型：
--
作者：
M. Nakagawa;T. Nishida
Lecithin-cholesterol acyltransferase in human plasma catalyzes the formation of cholesterol esters and lysolecithin primarily from choles terol and lecithin present in high density lipo proteins(1). The newly formed cholesterol esters are partially transferred from high to low density lipoproteins, and lysolecithin to albumin(2).Recently, Fielding et al. reported that both end products inhibit the acyltransferase reac tion and that the addition of albumin elimi nates the inhibitory effect of lysolecithin(3). The present communication describes quanti tative studies on the effect of lysolecithin and albumin on acyltransferase activity and deter mination of the equivalence ratio of lysoleci thin to albumin.
