Dengue in Southeast Asia: epidemiological characteristics and strategic challenges in disease prevention
Dengue in Southeast Asia: epidemiological characteristics and strategic challenges in disease prevention
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DOI：
10.1590/s0102-311x2009001300011
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发表时间：
2009-01-01
期刊：
影响因子：
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通讯作者：
Gubler, Duane J.
中科院分区：
文献类型：
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作者：
Ooi, Eng-Eong;Gubler, Duane J.
第二次世界大战期间和战后，登革热已成为东南亚的公共卫生负担，并且变得越来越重要，登革热/登革出血热的周期性流行逐渐变得更长和更频繁。尽管存在这种趋势，但在大多数东南亚国家，对这种媒介传播的病毒性疾病的监测仍然基本上是被动的，没有足够的实验室支持。我们在此回顾可能导致东南亚登革热流行病学变化的因素以及疾病预防的挑战。我们还讨论了积极监测登革热病毒的区域方法，重点关注病毒存在的城市地区，这可能是解决财政资源有限的办法，因为该地区大多数国家都是发展中经济体。区域性方法也将提高疾病预防成功的可能性，因为大量的人类旅行是导致登革热病毒地理传播的一个主要因素。
Dengue emerged as a public health burden in Southeast Asia during and following the Second World War and has become increasingly important, with progressively longer and more frequent cyclical epidemics of dengue fever/dengue hemorrhagic fever. Despite this trend, surveillance for this vector-borne viral disease remains largely passive in most Southeast Asian countries, without adequate laboratory support. We review here the factors that may have contributed to the changing epidemiology of dengue in Southeast Asia as well as challenges of disease prevention. We also discuss a regional approach to active dengue virus surveillance, focusing on urban areas where the viruses are maintained, which may be a solution to limited financial resources since most of the countries in the region have developing economies. A regional approach would also result in a greater likelihood of success in disease prevention since the large volume of human travel is a major factor contributing to the geographical spread of dengue viruses.