Polarized light-surface microscopy for description and classification of small and medium-sized congenital melanocytic naevi
Polarized light-surface microscopy for description and classification of small and medium-sized congenital melanocytic naevi
复制标题
DOI：
10.1080/00015550310016526
复制
发表时间：
2003-01-01
影响因子：
3.6
通讯作者：
Pellacani, G
中科院分区：
文献类型：
--
作者：
Seidenari, S;Martella, A;Pellacani, G
由于缺乏明确的临床标准来识别先天性病变，中小型先天性黑色素细胞痣的诊断一直是不确定的。我们的目的是描述小先天性黑色素细胞痣的特点，通过数字视频显微镜观察，目的是识别小先天性黑色素细胞痣或不同形态亚组的单一模式特征。然后，我们可以根据它们的宏观和表面微观方面进行分类。对154例先天性小黑色素细胞痣和150例后天性痣的数字图像进行了模式分析。小先天性黑色素细胞痣的新特征，如目标网络，目标球，目标血管和局灶性增厚的网络线，被确定，并进行细分的小先天性黑色素细胞痣到不同的亚组。判别分析能够区分先天性痣和寻常痣，敏感性为82.5%，特异性为64%。小先天性黑色素细胞痣可以通过数字视频显微镜和模式分析进行描述和分类。最重要的判别特征是靶网络、小球、滤泡和血管。这种分类可能是一个有用的工具，在后续的小先天性黑色素细胞痣。
Owing to a lack of well-defined clinical criteria for identifying congenital lesions, the diagnosis of small and medium-sized congenital melanocytic naevi is always uncertain. Our aim was to describe the features of small congenital melanocytic naevi, as observed by digital videomicroscopy, with the purpose of identifying single patterns characteristic of small congenital melanocytic naevi or different morphological subgroups. We could then perform a classification based on their macroscopic and surface microscopic aspects. Digital images referring to 154 small congenital melanocytic naevi and to 150 acquired naevi were examined for pattern analysis. New features characterizing small congenital melanocytic naevi, such as target network, target globules, target vessels and focal thickening of network lines, were identified, and a subdivision of small congenital melanocytic naevi into different subgroups was performed. Discriminant analysis enabled the distinction between congenital and common naevi with a sensitivity of 82.5% and a specificity of 64%. Small congenital melanocytic naevi can be described and classified by digital videomicroscopy and pattern analysis. The most important discriminant features are target network, small globules, follicles and vessels. This classification may represent a useful tool in the follow-up of small congenital melanocytic naevi.