Poly-l-lysine Functionalization of Single-Walled Carbon Nanotubes

Poly-l-lysine Functionalization of Single-Walled Carbon Nanotubes
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DOI:
10.1021/jp0471094
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发表时间:
2004-09
影响因子:
3.3
通讯作者:
Yuanjian Zhang;Jun Li;Yanfei Shen;Meijia Wang;Jinghong Li
Yuanjian Zhang;Jun Li;Yanfei Shen;Meijia Wang;Jinghong Li
中科院分区:
化学3区
文献类型:
--
作者:
Yuanjian Zhang;Jun Li;Yanfei Shen;Meijia Wang;Jinghong Li

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单壁碳纳米管(SWNTs)与生物相容性聚-L-赖氨酸共价官能化,这是有用的,在促进细胞粘附。单壁碳纳米管作为连接体,将多聚赖氨酸的活性氨基组装起来,为进一步衍生化,如连接生物活性分子提供了一个相对“友好”和“柔软”的环境。作为应用实例,通过进一步连接过氧化物酶,研究了关于该组装体的对H2 O2的放大生物传感。
Single-walled carbon nanotubes (SWNTs) were covalently functionalized with biocompatible poly-l-lysine, which is useful in promoting cell adhesion. SWNTs played an important role as connectors to assemble these active amino groups of poly-l-lysine, which provided a relative “friendly” and “soft” environment for further derivation, such as attaching bioactive molecules. As an application example, by further linking peroxidase, an amplified biosensing toward H2O2 concerning this assembly was investigated.