Interkingdom Transfer of the Acne-Causing Agent, Propionibacterium acnes, from Human to Grapevine
Interkingdom Transfer of the Acne-Causing Agent, Propionibacterium acnes, from Human to Grapevine
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DOI：
10.1093/molbev/msu075
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发表时间：
2014-05-01
影响因子：
10.7
通讯作者：
Rota-Stabelli, Omar
中科院分区：
文献类型：
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作者：
Campisano, Andrea;Ometto, Lino;Rota-Stabelli, Omar
在这里，我们报告了一个令人惊讶的，据我们所知，独特的例子，水平界间转移的人类机会致病菌（痤疮丙酸杆菌）的作物植物（驯化葡萄藤葡萄L.）。与大多数生物一样，人类与各种微生物建立了长期的共存关系，包括病原体和肠道相关细菌。研究这种关联的动力学的研究揭示了许多细菌宿主从家畜转移到人类的案例。然而，人们对人类和植物之间微生物共生体的交换知之甚少。荧光原位杂交定位痤疮丙酸杆菌在树皮，木质部纤维，更有趣的是，髓组织内。系统发育和种群遗传学分析表明，葡萄相关的痤疮丙酸杆菌作为专性内生菌的建立与最近的转移事件是相容的，可能是在新石器时代，葡萄藤被驯化。
Here, we report the surprising and, to our knowledge, unique example of horizontal interkingdom transfer of a human opportunistic pathogen (Propionibacterium acnes) to a crop plant (the domesticated grapevine Vitis vinifera L.). Humans, like most organisms, have established a long-lasting cohabitation with a variety of microbes, including pathogens and gut-associated bacteria. Studies which have investigated the dynamics of such associations revealed numerous cases of bacterial host switches from domestic animals to humans. Much less is, however, known about the exchange of microbial symbionts between humans and plants. Fluorescent in situ hybridization localized P. acnes in the bark, in xylem fibers, and, more interestingly, inside pith tissues. Phylogenetic and population genetic analyses suggest that the establishment of the grapevine-associated P. acnes as obligate endophyte is compatible with a recent transfer event, likely during the Neolithic, when grapevine was domesticated.