Patient-reported outcomes in cancer survivors: a population-wide cross-sectional study
Patient-reported outcomes in cancer survivors: a population-wide cross-sectional study
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DOI：
10.1007/s00520-017-3725-5
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发表时间：
2017-10-01
影响因子：
3.1
通讯作者：
Bishop, Jim
中科院分区：
文献类型：
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作者：
Jefford, Michael;Ward, Andrew C.;Bishop, Jim
关于癌症幸存者的生活经历，缺乏强有力的基于人口的数据。本研究评估了乳腺癌、结直肠癌或前列腺癌、非霍奇金淋巴瘤或黑色素瘤患者诊断后1年、3年和5年的生活质量（QoL）。研究人员评估了各种人口统计学和疾病相关因素与生活质量之间的关系，并进行了横断面邮寄调查。从基于人群的癌症登记处确定合格的参与者。患者报告的结果，包括生活质量，症状问题和信息需求收集使用验证questionnaire.Difficulties与所有生活质量领域之间的癌症幸存者相比，一般人群更普遍，特别是困难与日常活动（28比15%）和焦虑或抑郁（35比22%）。症状如睡眠困难，总是感到疲倦，注意力不集中和癌症复发的恐惧持续到诊断后5年。与生活质量下降相关的因素包括有另一个长期的健康状况，癌症没有完全响应治疗，没有或不确定有一个书面的护理计划，是female.Cancer幸存者的经验较差的生活质量和癌症相关的症状诊断后多年。这些结果支持进一步调查导致幸存者结果较差的因素，并加强对需要额外支持的幸存者的识别和干预战略。
There is a lack of robust population-based data regarding the lived experience of cancer survivors. This study assessed the quality of life (QoL) of survivors of breast, colorectal, or prostate cancer, non-Hodgkin lymphoma or melanoma 1, 3 and 5 years post-diagnosis. Associations between various demographic and disease-related factors and QoL were assessed.A cross-sectional postal survey was undertaken. Eligible participants were identified from a population-based cancer registry. Patient-reported outcomes including QoL, symptom issues and information needs were collected using validated questionnaires.Difficulties with all QoL domains were more prevalent amongst cancer survivors compared with the general population, particularly difficulties with usual activities (28 vs 15%) and anxiety or depression (35 vs 22%). Symptoms such as trouble sleeping, always feeling tired, trouble concentrating and fear of cancer recurrence persisted up to 5 years post-diagnosis. Factors associated with reduced QoL included having another long-standing health condition, cancer not responding fully to treatment, not having or not being certain of having a written care plan and being female.Cancer survivors experience inferior QoL and cancer-related symptoms for years following diagnosis. These results support further investigation into factors that contribute to poorer survivor outcomes and enhanced identification and intervention strategies for those requiring additional support.