Phantom evaluation of stacked-type dual-frequency 1-3 composite transducers: A feasibility study on intracavitary acoustic angiography
Phantom evaluation of stacked-type dual-frequency 1-3 composite transducers: A feasibility study on intracavitary acoustic angiography
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DOI：
10.1016/j.ultras.2015.06.009
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发表时间：
2015-12-01
期刊：
影响因子：
4.2
通讯作者：
Jiang, Xiaoning
中科院分区：
文献类型：
--
作者：
Kim, Jinwook;Li, Sibo;Jiang, Xiaoning
本文介绍了一种叠层式双频1-3压电复合换能器的体模评价结果，作为腔内声学造影的可行性研究。我们先前设计的血管内声学造影剂(6.5/30 MHz PMN-PT单晶换能器)的对比组织比(CTR)为12分贝，穿透深度为2.5 mm。为了改善穿透深度(>；3 mm)和对比组织比(>；12分贝)，我们评估了较低频率的2/14 MHz PZT 1-3复合换能器。给出了该换能器的超谐成像性能和声学血管成像关键参数的详细表征。在2/14 MHz频率下，发射机和接收机的-6分贝分数带宽分别为56.5%和41.8%，并在2 MHz处产生足够的峰值负压(>；1.5 Mpa)，以诱导微泡造影剂产生强烈的非线性谐波响应。在使用组织模拟体模和200微米纤维素微血管的体外声学造影研究中，检测到从5次到7次谐波的更高的微泡响应，信噪比为16分贝。微血管在二维图像中被分辨，轴向分辨率为615微米(是14 MHz波波长的5.5倍)，对比度与组织比为16分贝。这项可行性研究，包括对体模评估和关键参数的表征程序的详细解释，将对未来用于腔内声学造影的双频阵列换能器的开发有用。(C)2015爱思唯尔B.V.保留所有权利。
In this paper, we present phantom evaluation results of a stacked-type dual-frequency 1-3 piezoelectric composite transducer as a feasibility study for intracavitary acoustic angiography. Our previous design (6.5/30 MHz PMN-PT single crystal transducer) for intravascular contrast ultrasound imaging exhibited a contrast-to-tissue ratio (CTR) of 12 dB with a penetration depth of 2.5 mm. For improved penetration depth (> 3 mm) and comparable contrast-to-tissue ratio (> 12 dB), we evaluated a lower frequency 2/14 MHz PZT 1-3 composite transducer. Superharmonic imaging performance of this transducer and a detailed characterization of key parameters for acoustic angiography are presented. The 2/14 MHz arrangement demonstrated a -6 dB fractional bandwidth of 56.5% for the transmitter and 41.8% for the receiver, and produced sufficient peak-negative pressures (> 1.5 MPa) at 2 MHz to induce a strong nonlinear harmonic response from microbubble contrast agents. In an in-vitro contrast ultrasound study using a tissue mimicking phantom and 200 mu m cellulose microvessels, higher harmonic microbubble responses, from the 5th through the 7th harmonics, were detected with a signal-to-noise ratio of 16 dB. The microvessels were resolved in a two-dimensional image with a -6 dB axial resolution of 615 mu m (5.5 times the wavelength of 14 MHz waves) and a contrast-to-tissue ratio of 16 dB. This feasibility study, including detailed explanation of phantom evaluation and characterization procedures for key parameters, will be useful for the development of future dual-frequency array transducers for intracavitary acoustic angiography. (C) 2015 Elsevier B.V. All rights reserved.