The utility of volatile hydrocarboan analysis in cases of carbon monoxide poisoning
The utility of volatile hydrocarboan analysis in cases of carbon monoxide poisoning
复制标题
挥发性烃分析在一氧化碳中毒案例中的应用
DOI：
10.1007/bf01355520
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发表时间：
2005
影响因子：
2.1
通讯作者：
M. Kageura
中科院分区：
文献类型：
--
作者：
M. Morinaga;S. Kashimura;K. Hara;Y. Hieda;M. Kageura
本文报道了一种通过分析尸体血液中挥发性碳氢化合物来研究一氧化碳中毒情况的新方法。顶空气相色谱/质谱法用于证明烃。根据检测到的化合物，结果可分为四类。在建筑火灾案件中，现场没有发现助燃剂，血液中检测到苯，甲苯和苯乙烯。在受害者周围的火灾残骸中发现汽油的情况下，血液中检测到高水平的苯，甲苯，甲苯，二甲苯异构体，正己烷和正庚烷。在受害者周围的火灾残骸中发现煤油的情况下，在血液中检测到苯、甲苯、乙苯、二甲苯异构体、C9芳烃（正丙基苯、三甲基苯异构体）、正辛烷、正壬烷和正癸烷。在受害者被发现在充满废气的汽油燃料汽车内的情况下，发现了苯、甲苯、乙苯、二甲苯异构体、C9芳烃，但没有发现石油成分等脂肪烃。还对易燃材料的燃烧气体、废气、汽油蒸气和煤油蒸气进行了分析，以评价血液分析的结果。因此，提出了一些化合物作为区分吸入气体的指标，即在普通燃烧气体中的苯乙烯，在汽油情况下的正己烷和正庚烷以及苯、甲苯和C9-芳烃，在煤油情况下的正壬烷和正辛烷以及苯、甲苯和C9-芳烃，以及在废气情况下的苯、甲苯、C9-芳烃但不含脂肪族烃。
A new approach to investigate the circumstances relating to carbon monoxide intoxication by analysing volatile hydrocarbons in the blood of cadavers is reported. Headspace gas chromatography/mass spectrometry was used to demonstrate the hydrocarbons. The results can be characterized into four categories depending on the compounds detected. In construction fire cases where no accelerants were found at the scene benzene, toluene and styrene were detected in the blood. In cases where gasoline was found in the fire debris surrounding the victim, high levels of benzene, toluene, ethylbenzene, xylene isomers,n-hexane andn-heptane were detected in the blood. In cases where kerosene was found in the fire debris around the victim, benzene, toluene, ethylbenzene, xylene isomers, C9-aromatics(n-propylbenzene, trimethylbenzene isomers),n-octane,n-nonane andn-decane were detected in the blood. In cases where the victim was found inside a gasoline-fuelled automobile filled with exhaust gas, benzene, toluene, ethylbenzene, xylene isomers, C9-aromatics were found, but no aliphatic hydrocarbons such as components of petroleum. The analyses of the combustion gases of inflammable materials, exhaust gas, gasoline vapours and kerosene vapours were also performed to evaluate the results of the blood analyses. Consequently, some compounds are proposed as indicators to discriminate between inhaled gases i.e. styrene in common combustion gas,n-hexane andn-heptane as well as benzene, toluene and C9-aromatics in gasoline cases,n-nonane andn-octane as well as benzene, toluene and C9-aromatics in kerosene cases, and benzene, toluene, C9-aromatics but no aliphatic hydrocarbons in exhaust gas cases.