Differences in the erythropoiesis-hepcidin-iron store axis between hemoglobin H disease and β-thalassemia intermedia
Differences in the erythropoiesis-hepcidin-iron store axis between hemoglobin H disease and β-thalassemia intermedia
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DOI：
10.3324/haematol.2014.115733
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发表时间：
2015-05
期刊：
影响因子：
10.1
通讯作者：
R. Origa;M. Cazzola;Elisabetta Mereu;F. Danjou;S. Barella;N. Giagu;R. Galanello;D. Swinkels
中科院分区：
文献类型：
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作者：
R. Origa;M. Cazzola;Elisabetta Mereu;F. Danjou;S. Barella;N. Giagu;R. Galanello;D. Swinkels
由于红细胞生成无效而导致的先天性贫血，例如铁粒幼细胞性贫血、先天性红细胞生成障碍性贫血和中间型β地中海贫血（TI），通常与膳食铁吸收增加和进行性铁负荷有关，因此被定义为“铁负荷”
Congenital anemias due to ineffective erythropoiesis, such as sideroblastic anemia, congenital dyserythropoietic anemia and β-thalassemia intermedia (TI), are frequently associated with increased dietary iron absorption and progressive iron loading, and are therefore defined as “iron loading