AN ADJUSTABLE FETAL WEIGHT STANDARD

AN ADJUSTABLE FETAL WEIGHT STANDARD
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DOI:
10.1046/j.1469-0705.1995.06030168.x
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发表时间:
1995-09-01
影响因子:
7.1
通讯作者:
CHANG, A
CHANG, A
中科院分区:
医学1区
文献类型:
--
作者:
GARDOSI, J;MONGELLI, M;CHANG, A

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胎儿体重监测是产前保健的一个重要方面。为了构建一个单独可调的标准,我们开发了一个模型,将预测的出生体重与胎儿体重曲线联系起来,该曲线概述了在不复杂的妊娠中如何达到这个体重。通过对38 114例单胎、常规超声检查的足月分娩孕妇的出生体重数据库进行分析,得出了一个公式来描述每次妊娠时胎儿体重中位数与最佳足月体重的比例,并将第90和第10个百分位数曲线定义为正常范围。通过逐步多元回归分析,我们得出了影响我国人口足月儿出生体重的变量的系数。除胎龄和性别外,母亲身高、初诊体重、民族、产次和吸烟对新生儿出生体重均有显著的独立影响。在这个群体中,由于种族的差异似乎是生理性的。吸烟与出生体重的减少有关,而出生体重与母亲的体格无关,并与首次就诊时报告的每天吸烟数量有关。我们开发了一个软件程序,根据首次就诊时输入的怀孕变量计算调整后的正常胎儿尺寸范围。这可以打印成图表,用于产前发育监测。
The monitoring of fetal weight is an important aspect of antenatal care. To construct an individually adjustable standard, we developed a model to link the predicted birth weight to a fetal weight curve which outlines how this weight is to be reached in an uncomplicated pregnancy. A formula was derived which describes the median fetal weight at each gestation as a proportion of the optimal term weight, and also defines the 90th and 10th centile curves as normal limits.We analyzed a birth weight database of 38 114 singleton, routine ultrasound-dated pregnancies resulting in term deliveries. By stepwise multiple regression analysis, we derived coefficients for the factors that act as variables on term birth weight in our population. Apart from gestational age and sex, the maternal height, weight at first visit, ethnic group, parity and smoking all have significant and independent effects on birth weight. The variation due to ethnic group appears to be physiological in this population. Smoking is associated with a reduction in birth weight, which is independent of maternal physique and related to the number of cigarettes per day as reported at the first visit.We have developed a software program which calculates, on the basis of pregnancy variables entered at the first visit, an adjusted normal range for fetal size. This can be printed out as a chart and used for antenatal surveillance of growth.