Quercetin, Inflammation and Immunity.

Quercetin, Inflammation and Immunity.
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槲皮素,炎症和免疫。

DOI:
10.3390/nu8030167
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发表时间:
2016-03-15
期刊:
影响因子:
5.9
通讯作者:
Yin Y
Yin Y
中科院分区:
医学2区
文献类型:
--
作者:
Li Y;Yao J;Han C;Yang J;Chaudhry MT;Wang S;Liu H;Yin Y

文献摘要

被引文献

相似文献

体外和一些动物模型研究表明,槲皮素是一种来源于植物的多酚,具有广泛的生物学活性,包括抗癌、抗炎和抗病毒活性,以及减轻脂质过氧化、血小板聚集和毛细血管通透性。本文综述了槲皮素的理化性质、膳食来源、吸收、生物利用度和代谢,特别是对炎症和免疫功能的主要作用。根据体外和体内的研究结果,槲皮素具有良好的应用前景。然而,还需要进一步的研究来更好地确定槲皮素对炎症和免疫有益作用的作用机制。
In vitro and some animal models have shown that quercetin, a polyphenol derived from plants, has a wide range of biological actions including anti-carcinogenic, anti-inflammatory and antiviral activities; as well as attenuating lipid peroxidation, platelet aggregation and capillary permeability. This review focuses on the physicochemical properties, dietary sources, absorption, bioavailability and metabolism of quercetin, especially main effects of quercetin on inflammation and immune function. According to the results obtained both in vitro and in vivo, good perspectives have been opened for quercetin. Nevertheless, further studies are needed to better characterize the mechanisms of action underlying the beneficial effects of quercetin on inflammation and immunity.