Dynamic relationship between sympathetic nerve activity and renal blood flow: a frequency domain approach

Dynamic relationship between sympathetic nerve activity and renal blood flow: a frequency domain approach
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DOI:
10.1152/ajpregu.2001.281.1.r206
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发表时间:
2001-07-01
影响因子:
2.8
通讯作者:
Malpas, SC
Malpas, SC
中科院分区:
医学3区
文献类型:
--
作者:
Guild, SJ;Austin, PC;Malpas, SC

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人类的血压在0.1赫兹出现振荡,这被认为是由于交感神经活动(SNA)的振荡所致。然而,控制这种振荡的强度或频率的机制却知之甚少。本研究的目的是确定SNA和血管系统之间的动态关系。在6只戊巴比妥钠麻醉兔,电刺激肾交感神经,记录肾血流反应。将伪随机二进制序列(PRBS)应用于肾神经,该序列在感兴趣的频率(
Blood pressure displays an oscillation at 0.1 Hz in humans that is well established to be due to oscillations in sympathetic nerve activity (SNA). However, the mechanisms that control the strength or frequency of this oscillation are poorly understood. The aim of the present study was to define the dynamic relationship between SNA and the vasculature. The sympathetic nerves to the kidney were electrically stimulated in six pentobarbital-sodium anesthetized rabbits, and the renal blood flow response was recorded. A pseudo-random binary sequence (PRBS) was applied to the renal nerves, which contains equal spectral power at frequencies in the range of interest (