Regenerative medicine: a 2009 overview
Regenerative medicine: a 2009 overview
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DOI：
10.1111/j.1365-2796.2009.02157.x
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发表时间：
2009-10-01
影响因子：
11.1
通讯作者：
Lendahl, U.
中科院分区：
文献类型：
--
作者：
Andersson, E. R.;Lendahl, U.
快速发展的再生医学领域为基于细胞的治疗从脊髓损伤到血液学和神经系统疾病等一系列衰弱疾病提供了很大的希望。诱导多能干细胞(IPS)的突破性发现为疾病进展和患者特异性细胞移植的可能性提供了新的视角。在这篇综述中，我们首先简要介绍了再生医学领域的历史，然后讨论了再生医学的现状，重点讨论了胚胎干细胞和iPS细胞。为了跟上这一迅速发展的领域的步伐，《内科医学杂志》于2009年3月12日至13日在斯德哥尔摩卡罗林斯卡研究所举办了为期两天的研讨会，19位再生医学领域的顶尖科学家发表了演讲。在这篇综述中，我们讨论了研讨会，并介绍了六篇由研讨会演讲者撰写的评论文章，这些文章侧重于会议上讨论的一些主题。
The rapidly evolving field of regenerative medicine holds much promise for cell-based therapies for a range of debilitating conditions from spinal cord injury to haematological and neurological diseases. The groundbreaking discovery of induced pluripotent stem (iPS) cells has offered new perspectives on disease progression and the possibility of patient-specific cell transplants. In this review we first give a brief history of the field of regenerative medicine and then discuss the current state of regenerative medicine with a focus on embryonic stem cells and iPS cells. In order to keep abreast with this rapidly developing field, the Journal of Internal Medicine organized a 2-day Symposium, on March 12-13th 2009, at the Karolinska Insitute in Stockholm, which featured talks by 19 leading scientists in the field of regenerative medicine. In this review, we discuss the Symposium and introduce six accompanying review articles, by Symposium speakers, which focus on some of the topics discussed at the meeting.