Visible-Light-Mediated Access to Phosphate Esters
Visible-Light-Mediated Access to Phosphate Esters
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DOI：
10.1021/acs.orglett.0c01409
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发表时间：
2020-06-05
期刊：
影响因子：
5.2
通讯作者：
Lakhdar, Sami
中科院分区：
文献类型：
--
作者：
Inial, Alya;Morlet-Savary, Fabrice;Lakhdar, Sami
我们在这里报告了一个实际上简单的可见光催化方法，通过N-烷氧基吡啶盐和亚磷酸盐的组合在温和的条件下合成各种磷酸酯。反应的范围是广泛的，该协议已成功地应用于生物相关结构的合成。量子产率测量以及EPR实验允许提出合理的反应机制。
We report herein a practically simple visible-light photocatalytic approach for the synthesis of a large variety of phosphate esters through the combination of N-alkoxypyridinium salts and phosphites under mild conditions. The scope of the reaction is broad and the protocol was successfully applied to the synthesis of biologically relevant structures. Quantum yield measurements, as well as EPR experiments, allowed the suggestion of a reasonable reaction mechanism.