A case of esophageal squamous cell carcinoma metastatic to the breast
A case of esophageal squamous cell carcinoma metastatic to the breast
复制标题
食管鳞状细胞癌乳腺转移一例
DOI：
10.1007/bf02966908
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发表时间：
1999
期刊：
影响因子：
4
通讯作者：
Y. Kuwada
中科院分区：
文献类型：
--
作者：
K. Miyoshi;S. Fuchimoto;T. Ohsaki;Tatsuhiko Sakata;I. Takeda;Kenji Takahashi;T. Ohkawa;T. Murata;Y. Kuwada
乳房外恶性肿瘤转移到乳房是罕见的。食管癌转移的报道尤其少。我们报告一位44岁男性，患有晚期食道癌及左乳房肿瘤。组织学上证实为侵犯乳腺的鳞状细胞癌。ER、PgR和ErbB-2的免疫染色均为阴性。尸检时，在肺、肝、膈、腹膜、脊柱和纵隔淋巴结中发现转移性病变，没有转移到皮肤的证据。虽然转移性乳腺肿瘤很少是恶性肿瘤的初始体征，但重要的是要将转移与原发性乳腺癌区分开来，以避免不必要的冲突治疗。
Metastasis to the breast from extramammary malignancies is rare. There are especially few reports of metastasis from esophageal cancer. We report the pathological and autopsy findings of a 44-year-old man with advanced esophageal cancer and a left breast tumor. Squamous cell carcinoma invading the mammary glands was demonstrated histologically. Immunostains for ER, PgR, and ErbB-2 were negative. At autopsy, metastatic lesions were found in lung, liver, diaphragm, peritoneum, spine, and mediastinal lymph nodes, with no evidence of metastasis to the skin. While metastatic breast tumors are rarely the initial sign of malignancy, it is important to distinguish a metastasis from primary breast cancer to avoid unnecessary conflicting treatments.