A Smart Polysaccharide/Drug Conjugate for Photodynamic Therapy
A Smart Polysaccharide/Drug Conjugate for Photodynamic Therapy
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DOI：
10.1002/anie.201006038
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发表时间：
2011-01-01
影响因子：
16.6
通讯作者：
Lee, Eun Seong
中科院分区：
文献类型：
--
作者：
Park, So Young;Baik, Hye Jung;Lee, Eun Seong
更清晰的图像：一种新开发的多糖/药物结合物(见图)对PHA值的变化做出反应，并通过荧光成像确定可以穿透小鼠的HeLa肿瘤。它有可能用于光动力疗法，从而在不对周围组织产生有害影响的情况下靶向肿瘤。
Sharper image: A newly developed polysaccharide/drug conjugate (see picture) responds to changes in pHa value and was shown to penetrate HeLa tumors in mice as determined by fluorescence imaging. It has the potential to be used in photodynamic therapy, thereby targeting the tumor while having no detrimental effects on the surrounding tissue.