Synthesis of multisubstituted enamides via Pd-catalyzed chloroallylation of ynamides.
Synthesis of multisubstituted enamides via Pd-catalyzed chloroallylation of ynamides.
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DOI:
10.1021/jo2015278
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发表时间:
2011-09
期刊:
影响因子:
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通讯作者:
Zenghui Lu;Wei-Guang Kong;Zheliang Yuan;Xueyan Zhao;Gangguo Zhu
中科院分区:
文献类型:
--
作者:
Zenghui Lu;Wei-Guang Kong;Zheliang Yuan;Xueyan Zhao;Gangguo Zhu
An atom-economic approach to the regio- and stereoselective assembly of highly substituted enamides is described via the Pd-catalyzed chloroallylation of ynamides at room temperature, which offers a simple and practical alternative to the stereodefined multisubstituted enamides.