Murine gammaherpesvirus 68: a model for the study of gammaherpesvirus pathogenesis.
Murine gammaherpesvirus 68: a model for the study of gammaherpesvirus pathogenesis.
复制标题
DOI：
10.1016/s0966-842x(98)01306-7
复制
发表时间：
1998-07
影响因子：
15.9
通讯作者：
J. P. Simas;S. Efstathiou
中科院分区：
文献类型：
--
作者：
J. P. Simas;S. Efstathiou
鼠γ疱疹病毒68（MHV-68）是野生啮齿类动物的天然存在的疱疹病毒，并且在遗传上与人类疱疹病毒8和爱泼斯坦-巴尔病毒相关。MHV-68在实验室小鼠中建立急性和持续感染的能力为研究γ疱疹病毒发病机制的免疫学和病毒学方面提供了独特的机会。
Murine gammaherpesvirus 68 (MHV-68) is a naturally occurring herpesvirus of wild rodents and is genetically related to human herpesvirus 8 and Epstein-Barr virus. The ability of MHV-68 to establish acute and persistent infection within laboratory mice offers a unique opportunity to investigate immunological and virological aspects of gammaherpesvirus pathogenesis.