Radical resection of cardiac sarcoma
Radical resection of cardiac sarcoma
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DOI：
10.1055/s-2004-817809
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发表时间：
2004-04-01
影响因子：
1.5
通讯作者：
Scheld, HH
中科院分区：
文献类型：
--
作者：
Hoffmeier, A;Deiters, S;Scheld, HH
我们报告我们的经验与6例恶性肉瘤的心脏，并表明长期生存是可能的根治性切除术后。就诊时，6例患者（3例男性，3例女性）年龄为45.8 ± 20岁。3例患者自29.6 +/- 36.8个月起存活，无转移证据，3例患者在38 +/- 50.2个月后因远处转移死亡。通过影像学技术对肿瘤进行精确的术前定位是非常重要的。在某些情况下，根治性手术需要异位手术（自体移植）。如有必要，可以几乎完全切除右心，并以Fontan型循环的形式重建。从我们的观点来看，其他人建议的心脏移植是不合理的，因为预后并不好，供体器官太少。根治性切除的结果是有希望的，但新的治疗概念-特别是化疗概念-对于这些大多数中年或年轻患者是必要的。
We report on our experience with six patients with malignant sarcoma of the heart and show that long-term survival is possible after radical resection. At presentation, the 6 patients (3 male, 3 female) were 45.8 +/- 20 years old. Three patients are alive without evidence of metastases since 29.6 +/- 36.8 months, three patients died after 38 +/- 50.2 months due to distant metastases. Precise preoperative localization of the tumor by means of imaging techniques is very important. in some cases, radical surgery requires an ex situ procedure (autotransplantation). If necessary, the right heart can be resected almost completely, and reconstructed in the form of a Fontan-type circulation. A heart transplantation, as suggested by others, is not justified from our point of view, since prognosis is not better and donor organs are too rare. The results of radical resection are promising, but new concepts for treatment - in particular chemotherapy concepts - for these mostly middle-aged or young patients are required.