Heterotransplantation of mixed mesodermal tumor cells in nude mouse--histology of metastatic foci.
Heterotransplantation of mixed mesodermal tumor cells in nude mouse--histology of metastatic foci.
复制标题
裸鼠混合中胚层肿瘤细胞异种移植——转移灶的组织学。
DOI：
10.1016/0090-8258(87)90292-7
复制
发表时间：
1987
影响因子：
4.7
通讯作者：
H. Ishikawa
中科院分区：
文献类型：
--
作者：
I. Ishiwata;I. Ono;C. Ishiwata;T. Nakaguchi;M. Soma;M. Mukai;H. Ishikawa
混合性中胚叶肿瘤是癌和肉瘤的混合物。将来源于中胚叶混合瘤的HIRS-BM肿瘤细胞株移植于BALB/c裸鼠腹腔内，对转移灶进行组织学和细胞核学检查。HIRS-BM细胞产生类似原始肿瘤的混合中胚层肿瘤（腺癌和横纹肌肉瘤的混合物）。肉瘤与癌交界处未见正常间质组织。这些结果支持混合性中胚叶瘤的病因学说。
The mixed mesodermal tumor has an admixture of carcinoma and sarcoma. The HIRS-BM tumor cell line, derived from the mixed mesodermal tumor, was transplanted into the peritoneal cavity of BALB/c nude mice, and the metastatic foci were examined histologically and karyologically. The HIRS-BM cells produced mixed mesodermal tumors (admixture of adenocarcinoma and rhabdomyosarcoma) resembling the original tumor. The normal interstitial tissue was not present on the boundary of the sarcoma and carcinoma. These results support the combination theory as the cause of mixed mesodermal tumor.