Symptomatic intracranial tuberculoma developing during treatment of tuberculosis: a report of 10 patients and review of the literature.
Symptomatic intracranial tuberculoma developing during treatment of tuberculosis: a report of 10 patients and review of the literature.
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结核病治疗过程中出现的症状性颅内结核瘤：10 例患者的报告及文献综述。
DOI：
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
G. O'Mahony
中科院分区：
文献类型：
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作者：
R. Teoh;M. Humphries;G. O'Mahony
本文报告10例在治疗过程中发生的颅内结核。最初的感染是脑膜感染5例，麻疹感染3例，肺部感染2例，治疗后均好转。然而，治疗开始后10天至5个月(平均2个月)，出现新的神经症状和/或体征，导致识别出颅内结核。CT脑部扫描显示10例患者均有结核；5例有多个病灶，3例获得组织学证实。5名患者接受了早期(6周至5个月前)的CT脑部扫描，均未发现结核球。经抗结核药物治疗和控制颅内压升高后，5例患者完全恢复，3例患者有轻度神经功能障碍，2例患者预后判断为时过早。
Ten patients with intracranial tuberculomata which developed during treatment for tuberculosis are described. The initial infection was meningeal in five, miliary in three and pulmonary in two and all improved after treatment was started. However 10 days to five months (mean two months) after the start of treatment, new neurological symptoms and/or signs occurred that led to the recognition of intracranial tuberculomata. CT brain scans suggested tuberculomata in all 10 patients; there were several lesions in five and histological confirmation was obtained in three cases. Earlier CT brain scans (six weeks to five months before) were carried out in five patients and in none was a tuberculoma seen. After treatment with anti-tuberculous drugs and control of raised intracranial pressure when present, five patients made a full recovery, three were left with mild neurological deficit and in two it is too early to assess the outcome.