3.0 vs 1.5 T MRI in the detection of focal cartilage pathology - ROC analysis in an experimental model
3.0 vs 1.5 T MRI in the detection of focal cartilage pathology - ROC analysis in an experimental model
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DOI：
10.1016/j.joca.2005.08.002
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发表时间：
2006-01-01
影响因子：
7
通讯作者：
Majumdar, S
中科院分区：
文献类型：
--
作者：
Link, TM;Sell, CA;Majumdar, S
目的：使用接收机操作者特征（ROC）分析评估的诊断性能的三个软骨特异性MR序列在1.5和3 T在检测软骨病变创建在猪knee.Design：八十四软骨病变创建在27个猪膝关节标本在髌骨，内侧和外侧股骨和内侧和外侧胫骨软骨。使用脂肪饱和扰相梯度回波（SPGR）序列（平面内空间分辨率/层厚：0.20 × 0.39 mm（2）/1.5 mm）和两个脂肪饱和质子密度加权（PDw）序列（低空间分辨率：0.31 × 0.47 mm（2）/3 mm和高空间分辨率：0.20 × 0.26 mm（2）/2 mm）进行MR成像。由三名放射科医师使用五级置信度对图像进行独立分析，判断是否存在病变。结果：3位放射科医师的最高A（Z）值均为3 T时SPGR序列（A（Z）=0.84）和高分辨率（hr）PDw序列（A（Z）=0.79）。1.5T时相应的A（Z）值分别为0.77和0.69，1.5和3 T之间的差异有统计学意义（P
Objective: To use receiver operator characteristics (ROC) analysis for assessing the diagnostic performance of three cartilage-specific MR sequences at 1.5 and 3 T in detecting cartilage lesions created in porcine knees.Design: Eighty-four cartilage lesions were created in 27 porcine knee specimens at the patella, the medial and lateral femoral and the medial and lateral tibial cartilage. MR imaging was performed using a fat saturated spoiled gradient echo (SPGR) sequence (in plane spatial resolution/slice thickness: 0.20x0.39 mm(2)/1.5 mm) and two fat saturated proton density weighted (PDw) sequences (low spatial resolution: 0.31x0.47 mm(2)/3 mm and high spatial resolution: 0.20x0.26 mm(2)/2 mm). The images were independently analyzed by three radiologists concerning the absence or presence of lesions using a five-level confidence scale. Significances of the differences for the individual sequences were calculated based on comparisons of areas under ROC curves (A(Z)).Results: The highest A(Z)-values for all three radiologists were consistently obtained for the SPGR (A(Z)=0.84) and the high-resolution (hr) PDw (A(Z)=0.79) sequences at 3 T. The corresponding A(Z)-values at 1.5 T were 0.77 and 0.69; the differences between 1.5 and 3 T were statistically significant (P