Guidelines for the use of platelet transfusions
Guidelines for the use of platelet transfusions
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DOI：
10.1111/bjh.14423
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发表时间：
2017-02-01
影响因子：
6.5
通讯作者：
Tinegate, Hazel
中科院分区：
文献类型：
--
作者：
Estcourt, Lise J.;Birchall, Janet;Tinegate, Hazel
直到2007/8年，英国对血小板的需求稳定在每年22万ATD左右，2014/15年需求量同比增加至27.5万ATD，增长了25%。澳大利亚和美国的需求也出现了类似的增长。最近的一项审查考虑了这一急剧上升的原因，发现人口老龄化和血液恶性肿瘤发病率的增加（治疗强度、持续时间和生存时间的增加）是这一变化的主要原因（Estcourt 2014）。本指南旨在提供血小板输注的实用建议，以帮助临床医生决定何时支持是有益的，并减少不适当的使用。
The demand for platelets in England was stable at around 220,000 adult therapeutic doses (ATD) per year until 2007/8 at which point demand has increased year on year to 275,000 ATD in 2014/15, an increase of 25%. Similar rises in demand have been seen in Australia and the United States. A recent review which considered causes for this dramatic rise identified that an ageing population and an increase in the incidence of haematological malignancies (with increased treatment intensity, duration and survival) accounted for most of this change (Estcourt 2014). This guideline aims to provide practical advice on platelet transfusions to help clinicians to decide when support is expected to be beneficial and to reduce inappropriate use.