Patient Preference and Acceptance with Sodium Phosphate Tablet Preparation for Colonoscopy
Patient Preference and Acceptance with Sodium Phosphate Tablet Preparation for Colonoscopy
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DOI：
10.1007/s10620-008-0527-0
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发表时间：
2009-07-01
影响因子：
3.1
通讯作者：
Leighton, Jonathan A.
中科院分区：
文献类型：
--
作者：
Gurudu, Suryakanth R.;Li, Feng;Leighton, Jonathan A.
背景结肠镜检查被认为是筛查和预防结直肠癌的主要方法。然而，患者对该手术的接受度很差。患者的主要障碍是需要大体积（4-l）的术前结肠准备（聚乙二醇[PEG]溶液），这可能与不良味道有关。目的：确定既往使用PEG溶液进行结肠镜检查的患者对NaP片剂制剂的偏好和接受程度。方法邀请在过去12个月内使用标准4-L PEG溶液制剂进行结肠镜检查并计划再次进行结肠镜检查的患者参加本研究。对患者进行术前问卷调查。主要结局指标是患者是否表示偏好NaP片剂制剂而非之前的PEG溶液。结果完成研究的53名参与者中有35名（66%）更喜欢NaP片剂制剂而不是4-l PEG。大多数患者还表示，他们将再次使用NaP片剂制剂，并希望在下次结肠镜检查时有一种选择。结论：在先前使用4-l PEG制剂进行结肠清洁并参与本研究的患者中，66%的患者在结肠镜检查时更喜欢NaP片剂制剂而不是PEG制剂。
Background Colonoscopy is considered the primary procedure for colorectal cancer screening and prevention. However patient acceptance of this procedure has been poor. A major deterrent for patients is the need for a large-volume (4-l) preprocedure colonic preparation (polyethylene glycol [PEG] solution) that can be associated with a bad taste. Aim To determine patient preference and acceptance of the NaP tablet preparation in patients who have previously used PEG solutions for their prior colonoscopy exams. Methods Patients who had used a standard 4-l PEG solution preparation for a colonoscopy within the past 12 months and who were scheduled for a repeat colonoscopy were invited to participate in this study. A preprocedural questionnaire was administered to the patients. The primary outcome measure was whether the patient indicated a preference for the NaP tablet preparation over the previous PEG solution. Results Thirty-five of 53 participants (66%) who completed the study preferred the NaP tablet preparation over 4-l PEG. A majority of patients also indicated that they would use the NaP tablet preparation again and would like to have a choice of preparation for their next colonoscopy. Conclusions Among patients who previously used a 4-l PEG preparation for colon cleansing and participated in this study, 66% of patients preferred the NaP tablet preparation over the PEG preparation for their colonoscopy.