Aryl-substituted sulfonium betaines: Preparation and use in the epoxidation of aldehydes
Aryl-substituted sulfonium betaines: Preparation and use in the epoxidation of aldehydes
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DOI：
10.1021/jo061370u
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发表时间：
2006-10-13
影响因子：
3.6
通讯作者：
Standen, Michael C.
中科院分区：
文献类型：
--
作者：
Forbes, David C.;Amin, Sejal R.;Standen, Michael C.
羧甲基锍甜菜碱的热诱导脱羧导致原位形成相应的硫叶立德。使用核磁共振波谱测定了一系列芳基羧甲基锍甜菜碱盐的脱羧速率，并通过亚甲基转移到一系列醛形成环氧化物来评估叶立德生成和捕获的效率。
Thermally induced decarboxylation of carboxymethylsulfonium betaines results in formation of the corresponding sulfur ylides in situ. Decarboxylation rates for a range of arylcarboxymethylsulfonium betaine salts have been determined using NMR spectroscopy, and the efficiency of ylide generation and trapping has been evaluated via methylidene transfer to a range of aldehydes to form epoxides.