Helium ion therapy for choroidal melanoma.
Helium ion therapy for choroidal melanoma.
复制标题
氦离子治疗脉络膜黑色素瘤。
DOI：
10.1016/s0161-6420(83)34405-5
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发表时间：
1983
期刊：
影响因子：
13.7
通讯作者：
Hilton,GF
中科院分区：
文献类型：
--
作者：
Char,DH;Saunders,W;Castro,JR;Quivey,JM;Irvine,AR;Stone,RD;Crawford,JB;Barricks,M;Lonn,LI;Hilton,GF
采用氦离子带电粒子照射治疗脉络膜黑色素瘤82例。82例患者中有78例保持稳定或显示肿瘤缩小。46例患者中有45例在治疗后随访至少1年，显示肿瘤消退，平均肿瘤缩小约31%。未观察到肿瘤相关死亡。脉络膜黑色素瘤最有效的治疗方法尚不清楚。带电粒子外照射可能更适用，比放射性斑块或光凝具有更低的眼部发病率。
Eighty-two patients with choroidal melanomas were treated with helium ion charged particle irradiation. Seventy-eight of 82 patients have either remained stable or demonstrated tumor shrinkage. Forty-five of 46 patients followed for at least 1 year after therapy have demonstrated tumor regression with a mean tumor shrinkage of approximately 31%. No tumor-related mortality has been observed. The most effective method of choroidal melanoma management is unclear. Charged particle external beam irradiation may be more applicable and have less ocular morbidity than either radioactive plaques or photocoagulation.