DIFFERENCES BETWEEN BLACK-AND-WHITE MEN IN CORRELATES OF HIGH-DENSITY-LIPOPROTEIN CHOLESTEROL
DIFFERENCES BETWEEN BLACK-AND-WHITE MEN IN CORRELATES OF HIGH-DENSITY-LIPOPROTEIN CHOLESTEROL
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DOI：
10.1093/oxfordjournals.aje.a115707
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发表时间：
1990-10-01
影响因子：
5
通讯作者：
DESTEFANO, F
中科院分区：
文献类型：
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作者：
FREEDMAN, DS;STROGATZ, DS;DESTEFANO, F
虽然社会经济地位与白色美国人的高密度脂蛋白胆固醇水平呈正相关，但有限的证据表明，黑人中可能存在负相关。1985-1986年，从3，562名白色和500名黑人男性中收集了年龄在31岁到45岁之间的数据，进一步研究了这些关联。总体而言，黑人的HDL胆固醇平均水平比白人高8 mg/dl，在每组中，水平与饮酒呈正相关，与克托莱指数和吸烟呈负相关。然而，在种族和教育成就之间观察到了统计学上显著的相互作用：在白色男性中，教育成就和HDL胆固醇水平之间没有相关性，但在黑人中存在负相关。例如，在没有完成高中学业的黑人和白色男性之间观察到高密度脂蛋白胆固醇水平的13毫克/分升（55对42毫克/分升）差异，但在大学毕业生中只观察到3毫克/分升的黑人过量（47对44毫克/分升）。大约40%的这种减少可以归因于吸烟，饮酒和相对体重的影响。这些结果表明，在美国黑人男性中经常发现的高密度脂蛋白胆固醇水平可能并不适用于所有社会阶层。其他特征，如身体活动和饮食，可能解释了不同种族与教育成就的不同联系。
Although socioeconomic status has been positively related to levels of high density lipoprotein (HDL) cholesterol in white Americans, limited evidence suggests that an inverse association may exist among blacks. These associations were further examined using data collected in 1985-1986 from 3,562 white and 500 black men who ranged in age from 31 to 45 years. Overall, mean levels of HDL cholesterol were 8 mg/dl higher among blacks than among whites and, in each group, levels were related positively to alcohol consumption and negatively to Quetelet index and cigarette smoking. A statistically significant interaction, however, was observed between race and educational achievement: no association was seen between educational echievement and levels of HDL cholesterol among white men, but there was an inverse association among blacks. For example, a 13 mg/dl (55 vs. 42 mg/dl) difference in levels of HDL cholesterol was observed between black and white men who did not complete high school, but only a 3 mg/dl black excess (47 vs. 44 mg/dl) was seen among college graduates. About 40 percent of this reduction could be attributed to the effects of cigarette smoking, alcohol consumption, and relative weight. These results indicate that the higher level of HDL cholesterol frequently found among black men in the United States may not apply to all social strata. Other characteristics, such as physical activity and diet, may account for the differing race-specific associations with educational achievement.