Technical problems in lung allotransplantation. Causes of pulmonary venous outflow obstruction.
Technical problems in lung allotransplantation. Causes of pulmonary venous outflow obstruction.
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同种异体肺移植中的技术问题。
DOI：
10.1001/archsurg.1969.01340160086020
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发表时间：
1969
影响因子：
--
通讯作者：
Eric W. Fonkalsrud
中科院分区：
文献类型：
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作者：
Stevens Gh;D. Rangel;Y. Yakeishi;Eric W. Fonkalsrud
本实验室在过去18个月内进行了大约100例犬和灵长类动物同种异体肺移植手术，经验表明，技术问题是导致大量移植失败的原因。在我们的80例犬同种异体肺移植中，超过50%的失败似乎是由于移植物静脉流出的完全或部分阻塞。至少遇到三种不同类型的静脉阻塞。梗阻的类型似乎与移植后的持续时间有关，可以分为急性、中度和慢性静脉流出道梗阻。材料与方法杂种犬80只，体重15 ~ 26 kg（33 ~ 57 lb）。另外80人被用作捐赠者，每个捐赠者的体重与其各自的受体相匹配。除了红细胞交叉配型
Experience in this laboratory with approximately 100 canine and primate lung allotransplantation operations over the past 18 months has made clear the fact that technical problems are the cause of a large number of graft failures. In our series of 80 canine lung allotransplants which have been examined postmortem, more than 50% of failures appeared to be due to complete or partial obstruction to venous outflow from the graft. At least three distinct types of venous obstruction were encountered. The type of obstruction appears to be related to the duration of the posttransplant period, and may be characterized as acute, intermediate, and chronic venous outflow obstruction. Materials and Methods Eighty mongrel dogs, weighing from 15 to 26 kg (33 to 57 lb), were the recipients in this series. Another 80 were used as donors, each donor matched in weight with its respective recipient. With the exception of erythrocyte cross matching,