The immunosuppressive effect of α-permethrin on Indian major carp, rohu (Labeo rohita Ham.)
The immunosuppressive effect of α-permethrin on Indian major carp, rohu (Labeo rohita Ham.)
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DOI：
10.1016/s1050-4648(03)00029-9
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发表时间：
2004
影响因子：
4.7
通讯作者：
A. K. Nayak;B. Das;M. Kohli;S. Mukherjee
中科院分区：
文献类型：
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作者：
A. K. Nayak;B. Das;M. Kohli;S. Mukherjee
研究了亚致死浓度的拟除虫菊酯α-二氯苯醚菊酯（3.05×10− 4 mg l−1）对印度大锦鲤（Labeo rohita）的免疫抑制作用。研究了不同浓度的α-氯菊酯对鲤鱼非特异性防御能力和血清酶活性的影响。α-氯菊酯暴露后，几种非特异性免疫反应和血清酶降低。罗胡血清的杀菌活性显着降低农药和细菌处理的鱼。免疫抑制组的谷草转氨酶（GOT）和谷丙转氨酶（GPT）活性升高。与阴性对照相比，在农药和细菌处理的鱼中血糖水平显著升高，Hb%显著降低。
The immunosuppressive effects of bath exposure to a sub lethal concentration of the synthetic pyrethroid α-permethrin (3.05×10−4mg l−1) in the Indian Major carp, Labeo rohita was studied after 45 days' exposure. In some groups, the effects of α-permethrin on non-specific defences and serum enzymes of carp were investigated after challenge with Aeromonas hydrophila. Several nonspecific immune responses and serum enzymes were reduced after exposure of α-permethrin. Bactericidal activity of rohu serum was reduced significantly in pesticide and bacteria treated fish. The Glutamic Oxaloacetate Transaminase (GOT) and Glutamic Pyruvate Transaminase (GPT) activity were increased in immunosuppressed fish. Blood glucose level was elevated significantly and Hb% was reduced significantly in pesticide and bacteria treated fishes as compared to the negative control.