Chemistry of Metalloproteins

Chemistry of Metalloproteins
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金属蛋白质化学

DOI:
10.1002/9781118802236
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发表时间:
2014
期刊:
影响因子:
2.6
通讯作者:
A. Addison
A. Addison
中科院分区:
化学3区
文献类型:
--
作者:
J. J. Stephanos;A. Addison

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在金属蛋白质科学中的全部问题作为一个问答指南,这本书检查了金属结合蛋白质的所有主要家族,提出了我们对它们的结构,物理化学和功能特性的最新理解。此外,它还介绍了金属蛋白质的新的和新兴的医学应用。读者将发现这一重要的生物无机化学研究领域的基础化学和生物学。金属蛋白质化学的特点是一个积木的方法,使读者掌握的基础知识,然后前进到更复杂的主题。这本书以生物无机化学和金属蛋白质的一般介绍开始。接下来,它涵盖:碱金属和碱土金属阳离子金属酶铜蛋白铁蛋白维生素B12叶绿素章丰富的说明,以帮助读者充分掌握所有的化学概念,管理金属蛋白的生物作用。此外,每一章都以一个建议的原始研究文章和评论的列表结束,以进一步调查个别主题。介绍我们最新的金属蛋白质的理解,金属蛋白质化学推荐给学生和研究人员在配位化学,生物学和医学。蛋白质和肽科学的威利系列的每一卷都涉及该领域的一个特定方面,回顾了最新的发现并提出了广泛的观点。这一系列的卷构成了生物化学家、生物化学家、分子生物学家、遗传学家、细胞生物学家和生理学家以及对蛋白质和肽有兴趣的药物设计和开发、蛋白质组学和分子医学研究人员的基本阅读。
Addresses the full gamut of questions in metalloprotein science Formatted as a question-and-answer guide, this book examines all major families of metal binding proteins, presenting our most current understanding of their structural, physicochemical, and functional properties. Moreover, it introduces new and emerging medical applications of metalloproteins. Readers will discover both the underlying chemistry and biology of this important area of research in bioinorganic chemistry. Chemistry of Metalloproteins features a building block approach that enables readers to master the basics and then advance to more sophisticated topics. The book begins with a general introduction to bioinorganic chemistry and metalloproteins. Next, it covers: Alkali and alkaline earth cations Metalloenzymes Copper proteins Iron proteins Vitamin B12 Chlorophyll Chapters are richly illustrated to help readers fully grasp all the chemical concepts that govern the biological action of metalloproteins. In addition, each chapter ends with a list of suggested original research articles and reviews for further investigation of individual topics. Presenting our most current understanding of metalloproteins, Chemistry of Metalloproteins is recommended for students and researchers in coordination chemistry, biology, and medicine. Each volume of the Wiley Series in Protein and Peptide Science addresses a specific facet of the field, reviewing the latest findings and presenting a broad range of perspectives. The volumes in this series constitute essential reading for biochemists, biophysicists, molecular biologists, geneticists, cell biologists, and physiologists as well as researchers in drug design and development, proteomics, and molecular medicine with an interest in proteins and peptides.