New clinical index for drug-induced gingival overgrowth.
New clinical index for drug-induced gingival overgrowth.
复制标题
药物引起的牙龈过度生长的新临床指标。
DOI：
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发表时间：
1999
影响因子：
1.9
通讯作者：
R. Caffesse
中科院分区：
文献类型：
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作者：
E. Inglés;J. Rossmann;R. Caffesse
使用导致牙龈过度生长的药物的患者人数正在迅速增加。正在进行的器官移植数量的巨大增加，每个都需要选择免疫抑制药物环孢霉素进行治疗，这在牙龈组织的管理中产生了新的困境。此外，环孢霉素引起的高血压通常用钙通道阻滞剂治疗，如硝苯地平，两种药物协同作用诱导牙龈过度生长。目前，该专业缺乏一个定义明确且易于使用的临床指标来分类过度生长的牙龈组织。本文介绍了一个全面的，但简单的，评分系统，扩大组织，可提供指导临床医生和标准化的评价。该系统还可以为药物性牙龈增生的最佳手术治疗时间提供指导。
The numbers of patients using medications that induce gingival overgrowth are expanding rapidly. The tremendous increase in the number of organ transplants being performed, each requiring treatment with the immunosuppressive drug of choice, cyclosporine, has created a new dilemma in management of the gingival tissues. Additionally, cyclosporine-induced hypertension is frequently treated with calcium channel blockers, such as nifedipine, both drugs acting synergistically to induce gingival overgrowth. At present, the profession lacks a well-defined and easy-to-use clinical index for classifying overgrown gingival tissue. This article describes a comprehensive, yet simple, scoring system for enlarged tissues that may provide direction to the clinician and standardize evaluation. This system may also give guidance for the most appropriate time for surgical treatment of drug-induced gingival overgrowth.